Aberrant hippocampal mossy fiber sprouting correlates with greater NMDAR2 receptor staining.

@article{Mathern1996AberrantHM,
  title={Aberrant hippocampal mossy fiber sprouting correlates with greater NMDAR2 receptor staining.},
  author={Gary W. Mathern and Joao Pereira Leite and Thomas L. Babb and James K. Pretorius and Philip a. Kuhlman and Daniel Mendoza and Itzhak Fried and Am{\'e}rico Ceiki Sakamoto and Jo{\~a}o Alberto Assirati and P. David Adelson and Warwick J. Peacock},
  journal={Neuroreport},
  year={1996},
  volume={7 5},
  pages={1029-35}
}
This study determined in temporal lobe epilepsy patients and rats injected with intrahippocampal kainate (KA) whether fascia dentata molecular layer mossy fiber sprouting was associated with increases in NMDAR2 immunoreactivity (IR). Patients with hippocampal sclerosis (n = 11) were compared with those with temporal mass lesions (n = 7) and material obtained at autopsies (n = 4); and unilateral KA-injected rat hippocampi (n = 7) were compared with the contralateral saline-injected side and non… CONTINUE READING