Aberrant expression of long noncoding RNA PVT1 and its diagnostic and prognostic significance in patients with gastric cancer.

@article{Yuan2016AberrantEO,
  title={Aberrant expression of long noncoding RNA PVT1 and its diagnostic and prognostic significance in patients with gastric cancer.},
  author={Chun-ling Yuan and Haitao Li and Li-xin Zhu and Zhuoqi Liu and Jerry Zhou and Yongqian Shu},
  journal={Neoplasma},
  year={2016},
  volume={63 3},
  pages={
          442-9
        }
}
Emerging evidences indicate that dysregulated long noncoding RNAs (lncRNAs) are implicated in cancer tumorigenesis and progression and might be used as diagnosis and prognosis biomarker, or potential therapeutic targets. LncRNA PVT1 has been reported to be upregulated in diverse human cancers; however, its clinical significance in gastric cancer (GC) remains elusive. This study was to evaluate the expression of PVT1 in GC and further explore its clinical significance.Previous microarray… CONTINUE READING
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