Aberrant expression of immunoglobulin mRNA in bovine leukemia virus-infected cattle.


Our objective was to determine whether bovine leukemia virus (BLV) integration and expression affect the expression of host genes that function in immune responses and cell proliferation. Freshly isolated mlgM+ cells obtained from BLV-infected cows with persistent lymphocytosis (PL) expressed increased Ig-mu mRNA and decreased mRNA for Ig-lambda relative to… (More)


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