Aberrant expression of erythropoietin in uterine leiomyoma: implications in tumor growth.

@article{Asano2015AberrantEO,
  title={Aberrant expression of erythropoietin in uterine leiomyoma: implications in tumor growth.},
  author={Ryoko Asano and Mikiko Asai-Sato and Yohei Miyagi and Taichi Mizushima and Makiko Koyama-Sato and Yoji Nagashima and Masataka Taguri and Hideya Sakakibara and Fumiki Hirahara and Etsuko Miyagi},
  journal={American journal of obstetrics and gynecology},
  year={2015},
  volume={213 2},
  pages={199.e1-8}
}
OBJECTIVE Myomatous erythrocytosis syndrome is a rare complication of uterine leiomyoma caused by erythropoietin (EPO) that is produced by tumor cells. We assessed the EPO expression in leiomyomas and investigated the effects of EPO on the tumor growth. STUDY DESIGN Tissue samples were collected from 114 patients with uterine leiomyomas who underwent myomectomy or hysterectomy in Yokohama City University Hospital. From 17 patients, the corresponding normal myometrium was also collected. All… CONTINUE READING