Aberrant Signaling Pathways in T-Cell Acute Lymphoblastic Leukemia

@inproceedings{Bongiovanni2017AberrantSP,
  title={Aberrant Signaling Pathways in T-Cell Acute Lymphoblastic Leukemia},
  author={Deborah Bongiovanni and Valentina Saccomani and Erich Piovan},
  booktitle={International journal of molecular sciences},
  year={2017}
}
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive disease caused by the malignant transformation of immature progenitors primed towards T-cell development. Clinically, T-ALL patients present with diffuse infiltration of the bone marrow by immature T-cell blasts high blood cell counts, mediastinal involvement, and diffusion to the central nervous system. In the past decade, the genomic landscape of T-ALL has been the target of intense research. The identification of specific genomic… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS