Aberrant G protein-receptor expression is associated with DNA methylation in aldosterone-producing adenoma.

Abstract

This study aimed to evaluate the methylation levels of G protein-coupled receptor (GPCR) related genes and the effects of methylation on mRNA expression levels in aldosterone-producing adenoma (APA). DNA methylation array and transcriptome analysis were applied in non-functioning adrenocortical adenoma (NFA) and APA. We investigated 192 GPCR-related genes… (More)
DOI: 10.1016/j.mce.2017.08.019

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