Aberrant ADAM10 expression correlates with osteosarcoma progression


BACKGROUND Osteosarcoma is the most common type of bone cancer and is notorious for its rapid progression. The Notch signaling pathway has recently been shown to be involved in osteosarcoma. As a major sheddase of Notch receptors, ADAM10 has been implicated in many types of cancers, but its role in osteosarcoma has not been investigated. Previous studies… (More)
DOI: 10.1186/2047-783X-19-9


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