Aberrant, highly hyperdiploid cells in human papillomavirus-positive, abnormal cytologic samples are associated with progressive lesions of the uterine cervix.

@article{Bollmann2005AberrantHH,
  title={Aberrant, highly hyperdiploid cells in human papillomavirus-positive, abnormal cytologic samples are associated with progressive lesions of the uterine cervix.},
  author={Reinhard Bollmann and G{\'a}bor M{\'e}hes and Norbert Speich and Christoph Schmitt and Magdolna Bollmann},
  journal={Cancer},
  year={2005},
  volume={105 2},
  pages={96-100}
}
BACKGROUND Infection with oncogenic-type human papillomavirus (HPV) and consecutive cytologic abnormalities of the uterine cervix precede the evolution of carcinoma. However, the specificity of both changes is too low to predict the true malignant potential of the change in a given time point, because the majority of the HPV infections revert to normal with time. In preliminary studies, the authors demonstrated that, among many dysregulatory phenomena at the cytologic level, the occurrence of… CONTINUE READING