Abemaciclib for the treatment of breast cancer.

  title={Abemaciclib for the treatment of breast cancer.},
  author={Takeshi Kotake and Masakazu Toi},
  journal={Expert opinion on pharmacotherapy},
  volume={19 5},
INTRODUCTION There have been numerous clinical trials of CDK4/6 inhibitors performed on various carcinomas including breast cancer. One such inhibitor tested and which has ongoing clinical trials for breast cancer is abemaciclib. Abemaciclib is a molecular-targeted agent that targets basic cell cycle regulatory mechanisms. Areas covered: This review discusses the available clinical data and ongoing clinical trials of abemaciclib in breast cancer. Expert opinion: Abemaciclib has demonstrated a… CONTINUE READING


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