Abdominal rubber drain piece aggravates intra-abdominal sepsis in the rat.

@article{Guo1994AbdominalRD,
  title={Abdominal rubber drain piece aggravates intra-abdominal sepsis in the rat.},
  author={Wenmin Guo and Vasile Soltesz and Jin Wen Ding and Roger Will{\'e}n and Xinfeng Liu and Roland I Andersson and Stig Bengmark},
  journal={European journal of clinical investigation},
  year={1994},
  volume={24 8},
  pages={540-7}
}
Biomaterials in the peritoneal cavity disrupt the physiology of the host and may cause bacterial translocation. The current study was performed to determine whether biomaterials exacerbate intra-abdominal infections. Adult male rats were divided into four groups: group 1, celiotomy+intraperitoneal (i.p.) saline; group 2, celiotomy+i.p. Escherichia coli (3 x 10(8) cfu); group 3, i.p. rubber+i.p. saline; and group 4, i.p. rubber+i.p. E. coli (3 x 10(8) cfu). Twelve h after the challenge, enteric… CONTINUE READING