Abdominal aortic aneurysms and diabetes mellitus.

  title={Abdominal aortic aneurysms and diabetes mellitus.},
  author={Kalliopi Pafili and Ioanna Gouni-Berthold and Nikolaos Papanas and Dimitri P. Mikhailidis},
  journal={Journal of diabetes and its complications},
  volume={29 8},
There is accumulating evidence that risk profiles differ between coronary artery disease and abdominal aortic aneurysms (AAAs). However, diabetes mellitus (DM) appears to be negatively associated with AAA formation. The underlying mechanisms for this negative relationship are far from defined, but may include: increased arterial wall matrix formation via advanced glycation end products; suppression of plasmin and reduction of levels and activity of matrix metalloproteinases (MMP)-2 and 9… CONTINUE READING
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