Abdominal adiposity and the polycystic ovary syndrome.

  title={Abdominal adiposity and the polycystic ovary syndrome.},
  author={H{\'e}ctor F Escobar-Morreale and J L San Mill{\'a}n},
  journal={Trends in endocrinology and metabolism: TEM},
  volume={18 7},
Abdominal adiposity, overweightness and obesity are frequently present in patients with polycystic ovary syndrome (PCOS). A large body of evidence suggests that abdominal adiposity and the resulting insulin resistance contribute to ovarian and, possibly, adrenal hyperandrogenism. However, androgen excess itself might also contribute to abdominal fat deposition in hyperandrogenic women. Recent genomic and proteomic analyses of visceral fat from PCOS patients have detected differences in gene… CONTINUE READING