Abacavir and didanosine induce the interaction between human leukocytes and endothelial cells through Mac-1 upregulation.

@article{Pablo2010AbacavirAD,
  title={Abacavir and didanosine induce the interaction between human leukocytes and endothelial cells through Mac-1 upregulation.},
  author={Carmen de Pablo and Samuel Orden and Nadezda Apostolova and Amando Blanquer and Juan V Esplugues and {\'A}. Carrillo {\'A}lvarez},
  journal={AIDS},
  year={2010},
  volume={24 9},
  pages={1259-66}
}
OBJECTIVE Abacavir and didanosine are nucleoside reverse transcriptase inhibitors (NRTI) widely used in therapy for HIV-infection but which have been linked to cardiovascular complications. The objective of this study was to analyze the effects of clinically relevant doses of abacavir and didanosine on human leukocyte-endothelium interactions and to compare them with those of other NRTIs. DESIGN AND METHODS The interactions between human leukocytes - specifically peripheral blood… CONTINUE READING

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