Ab initio reconstruction and experimental design for cryo electron microscopy

Abstract

A statistical model for the object and the complete image formation process in cryo electron microscopy of viruses is presented. Using this model, maximum-likelihood reconstructions of the three-dimensional (3-D) structure of viruses are computed using the expectation maximization algorithm, and alternative experimental designs are evaluated based on Cramer… (More)
DOI: 10.1109/18.857786

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Statistics

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