Ab initio protein structure prediction results using a simple distance geometry-based method

Abstract

An approach to ab initio protein tertiary structure prediction based on building and scoring libraries of folds was tested at the CASP3 experiment. We present blind predictions for five helical targets varying in length from 31 to 114 residues. Our method was able to predict most of each structure correctly to about 6 Å Cα root-meansquare deviation (RMSD… (More)

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