AWARD NUMBER: W81XWH-13-1-0200 TITLE: Role of Klotho in Osteoporosis and Renal Osteodystrophy

@inproceedings{Lanske2014AWARDNW,
  title={AWARD NUMBER: W81XWH-13-1-0200 TITLE: Role of Klotho in Osteoporosis and Renal Osteodystrophy},
  author={Beate Lanske},
  year={2014}
}
Klotho acts as a co-receptor for and dictates tissue specificity of circulating FGF23. FGF23 inhibits PTH secretion, and reduced Klotho abundance is considered a pathogenic factor in renal secondary hyperparathyroidism. To dissect the role of parathyroid gland resident Klotho in health and disease, we generated mice with a parathyroid-specific Klotho… CONTINUE READING