• Corpus ID: 6077878

AUT 1 , a Gene Essential for Autophagocytosis in the Yeast Saccharomyces cerevisiae

  title={AUT 1 , a Gene Essential for Autophagocytosis in the Yeast Saccharomyces cerevisiae},
  author={Martin Schlumpberger and Elke Schaeffeler and Michael Straub and Monika Bredschneider and Dieter Heinrich Wolf and Michael Thumm},
Autophagocytosis is a starvation-induced process responsible for transport of cytoplasmic proteins to the vacuole. In Saccharomyces cerevisiae, autophagy is characterized by the phenotypic appearance of autophagic vesicles inside the vacuole of strains deficient in proteinase yscB. The AUT1 gene, essential for autophagy, was isolated by complementation of the sporulation deficiency of a diploid aut1-1 mutant strain by a yeast genomic library and characterized. AUT1 is located on the right arm… 

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  • Biology, Chemistry
    The Journal of cell biology
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