AURANOFIN INCREASES APOPTOSIS AND ISCHAEMIA–REPERFUSION INJURY IN THE RAT ISOLATED HEART

@article{Venardos2004AURANOFINIA,
  title={AURANOFIN INCREASES APOPTOSIS AND ISCHAEMIA–REPERFUSION INJURY IN THE RAT ISOLATED HEART},
  author={Kylie M Venardos and Glenn J. Harrison and John P. Headrick and Anthony V. Perkins},
  journal={Clinical and Experimental Pharmacology and Physiology},
  year={2004},
  volume={31}
}
1. Auranofin, an antirheumatic gold compound, is an inhibitor of selenocysteine enzymes, such as thioredoxin reductase and glutathione peroxidase. These enzymes play an important role in protecting cardiac tissue from oxidative stress generated during ischaemia–reperfusion. 
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