ATX3, ATX4, and ATX5 Encode Putative H3K4 Methyltransferases and Are Critical for Plant Development.

@article{Chen2017ATX3AA,
  title={ATX3, ATX4, and ATX5 Encode Putative H3K4 Methyltransferases and Are Critical for Plant Development.},
  author={Li-Qun Chen and Jin-Hong Luo and Zhen-Hai Cui and Ming L. Xue and Li Chun Wang and Xiaoyu Zhang and Wojciech P. Pawlowski and Yan He},
  journal={Plant physiology},
  year={2017},
  volume={174 3},
  pages={
          1795-1806
        }
}
Methylation of Lys residues in the tail of the H3 histone is a key regulator of chromatin state and gene expression, conferred by a large family of enzymes containing an evolutionarily conserved SET domain. One of the main types of SET domain proteins are those controlling H3K4 di- and trimethylation. The genome of Arabidopsis (Arabidopsis thaliana) encodes 12 such proteins, including five ARABIDOPSIS TRITHORAX (ATX) proteins and seven ATX-Related proteins. Here, we examined three until-now… CONTINUE READING
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