ATPgammaS enhances the production of inflammatory mediators by a human dermal endothelial cell line via purinergic receptor signaling.

Abstract

Adenosine 5'-triphosphate (ATP) affects multiple intra- and extracellular processes, including vascular tone and immune responses. Microvascular endothelial cells (EC) play a central role in inflammation by recruitment of inflammatory cells from blood to tissues. We hypothesized that ATP (secreted by neurons and/or released after perturbation of cutaneous… (More)

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@article{Seiffert2006ATPgammaSET, title={ATPgammaS enhances the production of inflammatory mediators by a human dermal endothelial cell line via purinergic receptor signaling.}, author={Kristina Seiffert and Wei Ding and John A. Wagner and Richard D Granstein}, journal={The Journal of investigative dermatology}, year={2006}, volume={126 5}, pages={1017-27} }