ATP-triggered unconventional secretion of GAPDH from macrophages: Its putative role as a modulator of inflammation

Abstract

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a key glycolytic enzyme that is predominantly localized in the cytoplasm. However, emerging evidence indicates that GAPDH is secreted from mammalian cells and performs some of its biological functions in the extracellular space. In particular, it has been reported that high levels of GAPDH are secreted… (More)

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Cite this paper

@inproceedings{Takenouchi2015ATPtriggeredUS, title={ATP-triggered unconventional secretion of GAPDH from macrophages: Its putative role as a modulator of inflammation}, author={Takato Takenouchi and Mitsutoshi Tsukimoto and Makoto Hashimoto and Hiroshi Kitani}, year={2015} }