ATP release through connexin hemichannels in corneal endothelial cells.

@article{Gomes2005ATPRT,
  title={ATP release through connexin hemichannels in corneal endothelial cells.},
  author={Priya Martina Gomes and Sangly P Srinivas and Willy van Driessche and Johan Vereecke and Bernard Himpens},
  journal={Investigative ophthalmology & visual science},
  year={2005},
  volume={46 4},
  pages={
          1208-18
        }
}
PURPOSE Intercellular Ca(2+) wave propagation is a distinct form of cell-cell communication. In corneal endothelial cells, intercellular Ca(2+) wave propagation evoked by a point mechanical stimulus (PMS) is partially mediated by adenosine triphosphate (ATP) release and subsequent activation of P2Y receptors. This study was conducted to investigate the possibility that extrajunctional connexons (hemichannels) play a role in ATP release during PMS-induced Ca(2+) wave propagation in bovine… CONTINUE READING

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