ATP regulates oligodendrocyte progenitor migration, proliferation, and differentiation: involvement of metabotropic P2 receptors.

@article{Agresti2005ATPRO,
  title={ATP regulates oligodendrocyte progenitor migration, proliferation, and differentiation: involvement of metabotropic P2 receptors.},
  author={Cristina Agresti and M E Meomartini and Susanna Amadio and Elena Ambrosini and Cinzia Volont{\'e} and Francesca Aloisi and Sergio Visentin},
  journal={Brain research. Brain research reviews},
  year={2005},
  volume={48 2},
  pages={157-65}
}
Extracellular nucleotides act as potent signaling molecules in the neuron-glia and glia-glia communication, via the activation of specific ligand-gated P2X and G-protein-coupled metabotropic P2Y receptors. Most of the data available about the effects of P2 receptor activation in the CNS concern astrocytes, microglia, and neurons. To gain insights into the role of purinergic receptors in oligodendrocyte development, we characterized the expression and functional activity of P2 receptors in rat… CONTINUE READING