ATP is released from guinea pig ureter epithelium on distension.

  title={ATP is released from guinea pig ureter epithelium on distension.},
  author={Gillian E. Knight and Philippe Bodin and William C. de Groat and Geoffrey Burnstock},
  journal={American journal of physiology. Renal physiology},
  volume={282 2},
Distension of the perfused guinea pig ureter at pressures from 20 to 700 cmH(2)O increased the amount of ATP released from the epithelium in a pressure-dependent manner. During basal perfusion (40 microl/min), the perfusate contained 10 pmol/ml ATP; this increased 10- to 50-fold at various distending pressures. ATP was released from epithelial cells during distension as mechanical removal of the urothelium blocked release. No lactate dehydrogenase was detected in the perfusate, and scanning… 

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