ATP induces the release of IL-1 from LPS-primed cells in vivo.

Abstract

The secretion of IL-1 from murine macrophages in vitro is an inefficient process that is distinct from those of other cytokines such as IL-6. We have therefore studied this process in vivo to see if these differences are maintained. Intraperitoneal injection of LPS in mice induced production and release of IL-6 into the extracellular fluid (peritoneal… (More)

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@article{Griffiths1995ATPIT, title={ATP induces the release of IL-1 from LPS-primed cells in vivo.}, author={Roger Griffiths and Ethan J. Stam and Jonathan Downs and Ivan G. Otterness}, journal={Journal of immunology}, year={1995}, volume={154 6}, pages={2821-8} }