ATP-induced morphological changes in supporting cells of the developing cochlea

@article{Tritsch2010ATPinducedMC,
  title={ATP-induced morphological changes in supporting cells of the developing cochlea},
  author={Nicolas X. Tritsch and Ying-xin Zhang and Graham C R Ellis-Davies and Dwight E Bergles},
  journal={Purinergic Signalling},
  year={2010},
  volume={6},
  pages={155-166}
}
The developing cochlea of mammals contains a large group of columnar-shaped cells, which together form a structure known as Kölliker’s organ. Prior to the onset of hearing, these inner supporting cells periodically release adenosine 5′-triphosphate (ATP), which activates purinergic receptors in surrounding supporting cells, inner hair cells and the dendrites of primary auditory neurons. Recent studies indicate that purinergic signaling between inner supporting cells and inner hair cells… CONTINUE READING
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