ATP increases chemoattractant induced cyclic GMP accumulation in Dictyostelium discoideum

@inproceedings{Mato1978ATPIC,
  title={ATP increases chemoattractant induced cyclic GMP accumulation in Dictyostelium discoideum},
  author={Jose M. Mato},
  year={1978}
}
Abstract Changes in guanosine cyclic 3′,5′-monophosphate associated with adenosine cyclic 3′,5′-monophosphate and folic acid addition in the presence of ATP have been examined in Dictyostelium discoideum . Preincubation with 1 mM ATP had no effect on the basal cyclic GMP level but increased the cycli GMP accumulation in response to cylci AMP (5·10 −8 M) or folic acid (5·10 −6 M) 40–50%. ATP could not be replaced by ADP of 5′-adenylyliminodiphosphate. Because ATP has no effect on cyclic AMP… CONTINUE READING