ATP-evoked membrane responses inXenopus oocytes

@article{Lotan1986ATPevokedMR,
  title={ATP-evoked membrane responses inXenopus oocytes},
  author={Ilana Lotan and Nathan Dascal and Sasson Cohen and Yoram Lass},
  journal={Pfl{\"u}gers Archiv},
  year={1986},
  volume={406},
  pages={158-162}
}
Voltage-clamp technique and intracellular injections of drugs were used to study the adenosine triphosphate (ATP)-evoked depolarizing current response in theXenopus laevis oocytes. The depolarizing current was comprised of a fast transient component (D1) followed by a late long-lasting component (D2). It was carried mainly by Cl− ions. The depolarizing current was better elicited by ATP and ADP than by AMP or adenosine and was not blocked either by theophylline (0.2 mM) or by quinidine sulphate… CONTINUE READING

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