ATP-dependent chromatin remodeling enzymes: two heads are not better, just different.

@article{Racki2008ATPdependentCR,
  title={ATP-dependent chromatin remodeling enzymes: two heads are not better, just different.},
  author={Lisa R. Racki and Geeta J Narlikar},
  journal={Current opinion in genetics & development},
  year={2008},
  volume={18 2},
  pages={137-44}
}
ATP-dependent chromatin remodeling complexes enable rapid rearrangements in chromatin structure in response to developmental cues. The ATPase subunits of remodeling complexes share homology with the helicase motifs of DExx box helicases. Recent single-molecule experiments indicate that, like helicases, many of these complexes use ATP to translocate on DNA. Despite sharing this fundamental property, two key classes of remodeling complexes, the ISWI class and the SWI/SNF class, generate distinct… CONTINUE READING

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