ATP-binding cassette transporters are targets for the development of antibacterial vaccines and therapies.

@article{Garmory2004ATPbindingCT,
  title={ATP-binding cassette transporters are targets for the development of antibacterial vaccines and therapies.},
  author={Helen S Garmory and Richard W. Titball},
  journal={Infection and immunity},
  year={2004},
  volume={72 12},
  pages={6757-63}
}
ATP-binding cassette (ABC) transporters are widespread among living organisms and comprise one of the largest protein families. For example, components of ABC transporters are encoded by approximately 5% of the Escherichia coli and Bacillus subtilis genomes (47, 80). These transporters are found in all species and are evolutionarily related. However, they are functionally diverse and have roles in a wide range of important cellular functions. The different ABC transporters can be assigned to… CONTINUE READING

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