ATP-binding cassette transporter ABCG2 (BCRP) and ABCB1 (MDR1) variants are not associated with disease susceptibility, disease phenotype response to medical therapy or need for surgeryin Hungarian patients with inflammatory bowel diseases.

@article{Fischer2007ATPbindingCT,
  title={ATP-binding cassette transporter ABCG2 (BCRP) and ABCB1 (MDR1) variants are not associated with disease susceptibility, disease phenotype response to medical therapy or need for surgeryin Hungarian patients with inflammatory bowel diseases.},
  author={Simon Fischer and Peter L Lakatos and L{\'a}szl{\'o} P{\'e}ter Lakatos and Agot{\'a} Kovacs and Tam{\'a}s Moln{\'a}r and Istv{\'a}n Altorjay and M{\'a}ria Papp and Anik{\'o} Szilv{\'a}si and Zsolt Tulassay and J{\'a}nos Osztovits and J{\'a}nos Papp and P{\'a}l Demeter and Rich{\'a}rd Schwab and Attila Tordai and Hajnalka Andrikovics},
  journal={Scandinavian journal of gastroenterology},
  year={2007},
  volume={42 6},
  pages={
          726-33
        }
}
OBJECTIVE MDR1 (ABCB1), a member of the ATP-binding cassette (ABC) transporters, is an attractive candidate gene for the pathogenesis of inflammatory bowel diseases (IBD) and perhaps for response to therapy. Since limited data are available on MDR1 and ABCG2 polymorphisms in East European IBD patients, the aim of this study was to investigate ABCG2 and MDR1 variants and responses to medical therapy and/or disease phenotype in Hungarian patients. MATERIAL AND METHODS A total of 414 unrelated… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 20 CITATIONS

Proteins of the ABC Family and Inflammation

  • Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology
  • 2019