ATP as a biological hydrotrope

@article{Patel2017ATPAA,
  title={ATP as a biological hydrotrope},
  author={Avinash B Patel and Liliana Malinovska and Shambaditya Saha and J. Wang and S. Alberti and Yamuna Krishnan and A. Hyman},
  journal={Science},
  year={2017},
  volume={356},
  pages={753 - 756}
}
ATP boosts protein solubility Adenosine triphosphate (ATP) has well-characterized roles in providing energy for biochemical reactions within cells. Patel et al. find that ATP may also enhance protein solubility, which could help explain why such high concentrations of ATP are maintained in cells (see the Perspective by Rice and Rosen). Protein concentrations in cells can exceed 100 mg/ml. The authors found that ATP at concentrations found in cells could act as a hydrotrope to help solubilize… Expand
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