ATP-activated, high-molecular-mass proteinase-I from rat skeletal muscle is a cysteine proteinase-alpha 1-macroglobulin complex.

Abstract

From rat skeletal muscle tissue we have isolated and purified a proteolytic activity of molecular mass 750 kDa. The enzyme, designated 'proteinase I', which has been found to be located in capillaries of skeletal muscle tissue, catalyzes the hydrolysis of Z-Phe-Arg-MCA and [14C]methylcasein and this process is activated about 2-fold by ATP. As judged by SDS… (More)

Topics

Cite this paper

@article{Dahlmann1989ATPactivatedHP, title={ATP-activated, high-molecular-mass proteinase-I from rat skeletal muscle is a cysteine proteinase-alpha 1-macroglobulin complex.}, author={Burkhardt Dahlmann and Lothar Kuehn and Peter Heinrich and Heidrun Kirschke and Bernd Wiederanders}, journal={Biochimica et biophysica acta}, year={1989}, volume={991 2}, pages={253-62} }