ATP, glia and central respiratory control.

  title={ATP, glia and central respiratory control.},
  author={Joseph S. Erlichman and James C Leiter and Alexander V. Gourine},
  journal={Respiratory physiology & neurobiology},
  volume={173 3},
An increase in PCO(2) in the arterial blood triggers immediate release of ATP from the ventral chemosensory site(s) on the surface of the medulla oblongata. Systemic hypoxia in anesthetized rats was also associated with increased ATP release on the ventral medullary surface. During both hypoxia and hypercapnia, ATP and possibly other gliotransmitters released in the ventral medulla seemed to enhance cardiorespiratory responses to these stressors, and some of this ATP was proposed to be derived… CONTINUE READING


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Connexin 26 is responsible for ATP release underlying central CO2 chemosensitivity

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