ATOPIC DISORDERS AND ADULT CŒLIAC DISEASE

@article{Hodgson1976ATOPICDA,
  title={ATOPIC DISORDERS AND ADULT C{\OE}LIAC DISEASE},
  author={Humphrey Julian Francis Hodgson and A. E. Gent and Rebecca J Davies and Margaret E. Hodson},
  journal={The Lancet},
  year={1976},
  volume={307},
  pages={115-117}
}
A history of asthma, hay fever, and flexural eczema was significantly more common in patients with adult coeliac disease (A.C.D.) than in normal controls. Autoantibodies were also more common in A.C.D. First-degree relatives of A.C.D. patients were more likely than controls to have atopic disorders. A deficiency of local mucosal immunity due to abnormal IgA responses may underly this association between A.C.D. and atopy. 
Atopic disease and dermatitis herpetiformis
Patients with dermatitis herpetiformis were found to have an increased incidence of atopic disorders compared to an age and sex matched control group. The increase in incidence was statistically
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It is suggested that an autoimmune mechanism should be excluded in patients with this combination of celiac disease, keratoconjunctivitis sicca, and autoimmune thrombocytopenia.
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An 11-year-old boy with chronic diarrhea, glossitis, chronic dermatitis, and megaloblastic anemia who later developed Hodgkin's lymphoma is reported.
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In AD patients, CD prevalence was more than four times as high as in previously studied randomly selected schoolchildren in Estonia and the need for screening individuals with AD for CD in time to prevent long‐term complications is emphasized.
Celiac Disease and Dermatologic Manifestations: Many Skin Clue to Unfold Gluten-Sensitive Enteropathy
TLDR
The aim of this paper is to describe the skin diseases frequently associated with celiac disease, distinguishing them from those which have a relationship probably just coincidental.
Prevalence of silent coeliac disease in atopics.
  • D. Zauli, A. Grassi, +5 authors U. Volta
  • Medicine
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
  • 2000
TLDR
The present study shows, for the first time, that the prevalence of coeliac disease in atopics is 1%, which is significantly higher than that in the general Italian population and should be considered a condition at risk and atopic patients routinely screened by means of specific autoantibody testing.
Prevalence of Asthma and Allergic Rhinitis in Children with Celiac Disease
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The prevalence rates of asthma and allergic rhinitis in patients with celiac disease were not significantly higher when compared to the healthy controls.
Immunological abnormalities in coeliac disease and their response to dietary restriction. I. Serum immunoglobulins, antibodies and complement.
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Patients with coeliac disease on a normal diet had significantly raised IgA and low IgM and an increased prevalence of antibody to reticulin, smooth muscle and dietary protein and these abnormalities disappeared during the period of dietary restriction suggesting that they are disease epiphenomena rather than primary pathogenetic factors.
Familial Association between Coeliac Disease and Ulcerative Colitis: Preliminary Communication
TLDR
The relatives of patients with coeliac disease are at increased risk not only of developing coeliat disease but also ulcerative colitis, which provides further support for a possible role of a dietary allergen in the development of ulceratives colitis.
HLA antigens and atopy in children with coeliac disease.
TLDR
It is concluded that atopy predisposes to coeliac disease partly independently of the HLA-DR3 associated disease susceptibility gene(s), and that different mechanisms may operate in the pathogenesis in coeliasis disease patients with and without atopy.
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