ATLAS: Analysis Tools for Low-depth and Ancient Samples

@inproceedings{Link2017ATLASAT,
  title={ATLAS: Analysis Tools for Low-depth and Ancient Samples},
  author={Vivian Link and Athanasios Kousathanas and Krishna Ranganaden Veeramah and Christian Sell and Amelie Scheu and Daniel Wegmann},
  year={2017}
}
Post-mortem damage (PMD) obstructs the proper analysis of ancient DNA samples. Currently, PMD can only be addressed by adjusting sequencing quality scores or by removing potentially damaged data. Here we present ATLAS, a suite of methods to analyze ancient samples that properly account for PMD. It works directly from raw BAM files and contains all necessary methods to infer patterns of PMD, recalibrate base quality scores and accurately genotype ancient DNA, along with many other useful tools… CONTINUE READING
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SHOWING 1-10 OF 16 REFERENCES

Ancient DNA and human history.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2016
VIEW 1 EXCERPT

Early farmers from across Europe directly descended from Neolithic Aegeans.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2016

Separating endogenous ancient DNA from modern day contamination in a Siberian Neandertal.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2014

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