ATF6α stimulates cholesterogenic gene expression and de novo cholesterol synthesis.

Abstract

The activating transcription factor 6α (ATF6α) is a sensor of the endoplasmic reticulum stress response that regulates the expression of genes involved in the unfolded protein response. Here we found that forced expression of a constitutively active form of ATF6α, ATF6(N), stimulated the expression of cholesterogenic genes, including 3-hydroxy-3-methyl… (More)

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Cite this paper

@article{Maruyama2013ATF6SC, title={ATF6α stimulates cholesterogenic gene expression and de novo cholesterol synthesis.}, author={Ryuto Maruyama and Yuki Kamoshida and Makoto Shimizu and Jun Inoue and Ryuichiro Sato}, journal={Bioscience, biotechnology, and biochemistry}, year={2013}, volume={77 8}, pages={1734-8} }