AT1 receptor blocker added to ACE inhibitor provides benefits at advanced stage of hypertensive diastolic heart failure.

Abstract

Diastolic heart failure (DHF) has become a social burden; however, evidences leading to its therapeutic strategy are lacking. This study investigated effects of addition of angiotensin II type 1 receptor blocker (ARB) to angiotensin-converting enzyme inhibitor (ACEI) at advanced stage of DHF in hypertensive rats. Dahl salt-sensitive rats fed 8% NaCl diet… (More)

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@article{Yoshida2004AT1RB, title={AT1 receptor blocker added to ACE inhibitor provides benefits at advanced stage of hypertensive diastolic heart failure.}, author={Junichi Yoshida and Kazuhiro Yamamoto and Toshiaki Mano and Yasushi Sakata and Nagahiro Nishikawa and Mayu Nishio and Tomohito Ohtani and Takeshi Miwa and M. Hori and Tohru Masuyama}, journal={Hypertension}, year={2004}, volume={43 3}, pages={686-91} }