AT(1) receptor blockers prevent sympathetic hyperactivity and hypertension by chronic ouabain and hypertonic saline.

@article{Zhang2001AT1RB,
  title={AT(1) receptor blockers prevent sympathetic hyperactivity and hypertension by chronic ouabain and hypertonic saline.},
  author={J. Zhang and Frans H H Leenen Leenen},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2001},
  volume={280 3},
  pages={H1318-23}
}
Sympathetic hyperactivity and hypertension caused by chronic treatment with ouabain or sodium-rich artificial cerebrospinal fluid (aCSF) can be prevented by central administration of an angiotensin type 1 (AT(1)) receptor blocker. In the present study, we assessed whether, in Wistar rats, chronic peripheral treatment with the AT(1) receptor blockers… CONTINUE READING