Providing pharmaceutical care entails accepting responsibility for patients’ pharmacotherapeutic outcomes. Pharmacists can contribute to positive outcomes by educating and counseling patients to prepare and motivate them to follow their pharmacotherapeutic regimens and monitoring plans. The purpose of this document is to help pharmacists provide effective patient education and counseling. In working with individual patients, patient groups, families, and caregivers, pharmacists should approach education and counseling as interrelated activities. ASHP believes pharmacists should educate and counsel all patients to the extent possible, going beyond the minimum requirements of laws and regulations; simply offering to counsel is inconsistent with pharmacists’ responsibilities. In pharmaceutical care, pharmacists should encourage patients to seek education and counseling and should eliminate barriers to providing it. Pharmacists should also seek opportunities to participate in health-system patient-education programs and to support the educational efforts of other health care team members. Pharmacists should collaborate with other health care team members, as appropriate, to determine what specific information and counseling are required in each patient care situation. A coordinated effort among health care team members will enhance patients’ adherence to pharmacotherapeutic regimens, monitoring of drug effects, and feedback to the health system. ASHP believes these patient education and counseling guidelines are applicable in all practice settings—including acute inpatient care, ambulatory care, home care, and long-term care—whether these settings are associated with integrated health systems or managed care organizations or are freestanding. The guidelines may need to be adapted; for example, for use in telephone counseling or for counseling family members or caregivers instead of patients. Patient education and counseling usually occur at the time prescriptions are dispensed but may also be provided as a separate service. The techniques and the content should be adjusted to meet the specific needs of the patient and to comply with the policies and procedures of the practice setting. In health systems, other health care team members share in the responsibility to educate and counsel patients as specified in the patients’ care plans.