ASCORBIC ACID‐INDEPENDENT AND ASCORBIC ACID‐DEPENDENT COLLAGEN‐FORMING MECHANISMS *

@article{Gould1961ASCORBICAA,
  title={ASCORBIC ACID‐INDEPENDENT AND ASCORBIC ACID‐DEPENDENT COLLAGEN‐FORMING MECHANISMS *},
  author={B. S. Gould},
  journal={Annals of the New York Academy of Sciences},
  year={1961},
  volume={92}
}
  • B. S. Gould
  • Published 1961
  • Chemistry, Medicine
  • Annals of the New York Academy of Sciences
That ascorbic acid plays a definite role in collagen biosynthesis has been amply demonstrated by the fact that after relatively short withdrawal of ascorbic acid from the diets of ascorbic acid-dependent animals, collagen formation in healing wounds and in model systems, as in implanted polyvinyl sponges and in carrageenan granulomas, is markedly impaired. I t has also been demonstrated1a2 that ascorbic acid is essential to prevent the almost complete resorption of newly formed collagen as… Expand
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