AS03-adjuvanted versus non-adjuvanted inactivated trivalent influenza vaccine against seasonal influenza in elderly people: a phase 3 randomised trial.

@article{Mcelhaney2013AS03adjuvantedVN,
  title={AS03-adjuvanted versus non-adjuvanted inactivated trivalent influenza vaccine against seasonal influenza in elderly people: a phase 3 randomised trial.},
  author={J. Mcelhaney and J. Beran and Jeanne-Marie Devaster and Meral Esen and O. Launay and G. Leroux-Roels and G. Ru{\'i}z-Palacios and G. A. van Essen and A. Caplanusi and Carine Claeys and Christelle Durand and X. Duval and M. El Idrissi and A. Falsey and G. Feldman and S. Frey and Florence Galtier and Shinn-Jang Hwang and B. Innis and M. Kovac and P. Kremsner and S. Mcneil and A. Nowakowski and J. Richardus and Andrew F. Trofa and L. Oostvogels},
  journal={The Lancet. Infectious diseases},
  year={2013},
  volume={13 6},
  pages={
          485-96
        }
}
  • J. Mcelhaney, J. Beran, +23 authors L. Oostvogels
  • Published 2013
  • Medicine
  • The Lancet. Infectious diseases
  • BACKGROUND We aimed to compare AS03-adjuvanted inactivated trivalent influenza vaccine (TIV) with non-adjuvanted TIV for seasonal influenza prevention in elderly people. METHODS We did a randomised trial in 15 countries worldwide during the 2008-09 (year 1) and 2009-10 (year 2) influenza seasons. Eligible participants aged at least 65 years who were not in hospital or bedridden and were without acute illness were randomly assigned (1:1) to receive either AS03-adjuvanted TIV or non-adjuvanted… CONTINUE READING
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