ARNT2 Regulates Tumoral Growth in Oral Squamous Cell Carcinoma.

  title={ARNT2 Regulates Tumoral Growth in Oral Squamous Cell Carcinoma.},
  author={Yasushi Kimura and Atsushi Kasamatsu and Dai Nakashima and Masanobu Yamatoji and Yasuyuki Minakawa and Kazuyuki Koike and Kazuaki Fushimi and Morihiro Higo and Yosuke Endo-Sakamoto and Masashi Shiiba and Hideki Tanzawa and Katsuhiro Uzawa},
  journal={Journal of Cancer},
  volume={7 6},
Aryl hydrocarbon receptor nuclear translocator (ARNT) 2 is a transcriptional factor related to adaptive responses against cellular stress from a xenobiotic substance. Recent evidence indicates ARNT is involved in carcinogenesis and cancer progression; however, little is known about the relevance of ARNT2 in the behavior of oral squamous cell carcinoma (OSCC). In the current study, we evaluated the ARNT2 mRNA and protein expression levels in OSCC in vitro and in vivo and the clinical… CONTINUE READING