ARK5 promotes doxorubicin resistance in hepatocellular carcinoma via epithelial-mesenchymal transition.

@article{Xu2016ARK5PD,
  title={ARK5 promotes doxorubicin resistance in hepatocellular carcinoma via epithelial-mesenchymal transition.},
  author={Tao Xu and Jian Zhang and Wei Chen and Shengjing Pan and Xiao Zhi and Liang Wen and Yue Zhou and Bryan Wei Chen and Junyu Qiu and Yun Zhang and Qi Yang and Xinhua Feng and Xueli Bai and Tingbo Liang},
  journal={Cancer letters},
  year={2016},
  volume={377 2},
  pages={140-8}
}
AMP-activated protein kinase family member 5 (ARK5) overexpression has been reported in many human cancers, and ARK5 is associated with poor prognosis in hepatocellular carcinoma (HCC). However, whether ARK5 is involved in HCC chemoresistance is unclear. The present study aimed to investigate the role of ARK5 in HCC chemoresistance and the underlying… CONTINUE READING