ARA 290 relieves pathophysiological pain by targeting TRPV1 channel: Integration between immune system and nociception.

Abstract

ARA 290 is an erythropoietin-derived polypeptide that possesses analgesic and tissue protective effect in many diseases such as diabetes and cancer. The analgesic effect of ARA 290 is mediated by its anti-inflammatory and immunomodulatory functions, or more specifically, by targeting the innate repair receptor (IRR) to down-regulate inflammation to… (More)
DOI: 10.1016/j.peptides.2016.01.003

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