APPLICATION OF RESPONSE SURFACE METHODOLOGY IN MEDIUM COMPONENTS OPTIMIZATION TO ENHANCE SERRATIOPEPTIDASE PRODUCTION BY STREPTOMYCES HYDROGENANSMGS13

@inproceedings{Vanama2014APPLICATIONOR,
  title={APPLICATION OF RESPONSE SURFACE METHODOLOGY IN MEDIUM COMPONENTS OPTIMIZATION TO ENHANCE SERRATIOPEPTIDASE PRODUCTION BY STREPTOMYCES HYDROGENANSMGS13},
  author={Jyothi Vanama and Haritha Chintada and Girija Sankar Guntuku and Prabhakar Tadimalla},
  year={2014}
}
For enhanced production of Serratiopeptidase by an actinomycetestrain, Streoptomyces hydrogenans MGS13, optimization of fermentationmedium was initially carried out by conventional method of ‗one-factor-at-atime‘.Later it was optimized by applying response surface methodology.Interactions were studied with four variables viz. levels of dextrose, soyabean meal and inoculum & pH using Central Composite Design. This modelwas validated by conducting the experiments under the optimized conditions… CONTINUE READING

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