APOL1 polymorphisms and development of CKD in an identical twin donor and recipient pair.

@article{Kofman2014APOL1PA,
  title={APOL1 polymorphisms and development of CKD in an identical twin donor and recipient pair.},
  author={Tomek Kofman and Vincent Audard and C{\'e}line Narjoz and Olivier Gribouval and M de Go{\"u}yon Matignon and Claire Leibler and Dominique Desvaux and Philippe Lang and Philippe Grimbert},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  year={2014},
  volume={63 5},
  pages={816-9}
}
We report an occurrence of progressive loss of transplant function and ultimately transplant failure after living related kidney transplantation involving monozygotic twin brothers of Afro-Caribbean origin who were both heterozygous for the G1 and G2 kidney disease risk alleles in the APOL1 gene, which encodes apolipoprotein L-I. A 21-year-old man with end… CONTINUE READING