APOE polymorphism affects episodic memory among non demented elderly subjects.

  title={APOE polymorphism affects episodic memory among non demented elderly subjects.},
  author={Simona De Blasi and Alberto Montesanto and Cinzia Martino and Serena Dato and Francesco De Rango and Amalia Cecilia Bruni and Vincenzo Mari and Emidio Feraco and Giuseppe Passarino},
  journal={Experimental gerontology},
  volume={44 3},
The APOE epsilon4 allele has been associated with a number of neurodegenerative disorders e.g. Alzheimer's disease. Inconsistent results have been obtained for cognitive decline in 'normal' aging. We investigated whether specific aspects of cognitive decline were associated with APOE epsilon4 among 620 'healthy' elderly subjects living in Calabria, southern Italy. MMSE scores ranged from 11 to 30. A lower MMSE score was unrelated to APOE polymorphism, i.e. a global measure of cognition. However… CONTINUE READING


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Prospective Study of Pravastatin in the Elderly at Risk Group. Association between apolipoprotein E4 and cognitive decline in elderly adults

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