APOE genotype, ethnicity, and the risk of cerebral hemorrhage.

  title={APOE genotype, ethnicity, and the risk of cerebral hemorrhage.},
  author={Christophe Tzourio and Hisatomi Arima and Stephen Brian Harrap and Chris Anderson and Ophelia Godin and Michael Woodward and Bruce Neal and M G Bousser and J. W. T. Chalmers and François Cambien and Stephen MacMahon},
  volume={70 16},
OBJECTIVE The apolipoprotein E (APOE) polymorphism is an established risk factor for intracerebral hemorrhage (ICH) that is related to cerebral amyloid angiopathy in the white population. Among Asian populations, although ICH represents up to one third of all strokes and has high rates of mortality and morbidity, the role of the APOE polymorphism has not been well studied. METHODS The Perindopril Protection Against Recurrent Stroke Study (PROGRESS) was a randomized, double-blind, placebo… CONTINUE READING