APOE associated hemispheric asymmetry of entorhinal cortical thickness in aging and Alzheimer's disease.

@article{Donix2013APOEAH,
  title={APOE associated hemispheric asymmetry of entorhinal cortical thickness in aging and Alzheimer's disease.},
  author={Markus Donix and Alison C. Burggren and Maria Scharf and Kira Marschner and Nanthia A. Suthana and Prabha Siddarth and Allison K. Krupa and Michael Jones and Laurel Martin-Harris and Linda M. Ercoli and Karen J. Miller and Annett Werner and R{\"u}diger von Kummer and Cathrin Sauer and Gary W. Small and Vjera A. Holthoff and Susan Y. Bookheimer},
  journal={Psychiatry research},
  year={2013},
  volume={214 3},
  pages={212-20}
}
Across species structural and functional hemispheric asymmetry is a fundamental feature of the brain. Environmental and genetic factors determine this asymmetry during brain development and modulate its interaction with brain disorders. The e4 allele of the apolipoprotein E gene (APOE-4) is a risk factor for Alzheimer's disease, associated with regionally specific effects on brain morphology and function during the life span. Furthermore, entorhinal and hippocampal hemispheric asymmetry could… CONTINUE READING
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